A parasitic infection caused by the nematode loa loa. The vector in the transmission of this infection is the horsefly (tabanus) or the deerfly or mango fly (chrysops). The larvae may be seen just beneath the skin or passing through the conjunctiva. Eye lesions are not uncommon. The disease is generally mild and painless.
(12 Dec 1998)
Calabar swellings are localized infections where the parasite Loa Loa is secreting toxins. It is an immune reaction caused when the worms that reside in the subcutaneous tissue are injured by a minor or major force to the skin. The insides of the worm are then exposed to the immune system, and a powerful reaction ensues. Normally, the immune system does not detect the helminth until it is injured.
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