News from LufeeEuropean Medicines Agency Recommends Contraindication For Regranex In Patients With Any Pre-Existing Cancer(02-19-2010 08:59 PM)Following a review of the available data on a possible risk of cancer in patients using Regranex (becaplermin), from Janssen-Cilag International N.V., the European Medicines Agency has concluded that the medicine must not be used in patients who have any form of cancer... European Medicines Agency Recommends Contraindication For Regranex In Patients With Any Pre-Existing Cancer(02-19-2010 02:04 PM)Following a review of the available data on a possible risk of cancer in patients using Regranex (becaplermin), from Janssen-Cilag International N.V., the European Medicines Agency has concluded that the medicine must not be used in patients who have any form of cancer. A similar restriction previously applied, but only for patients who had a skin cancer close to the area where the gel was to be applied. Regranex is a gel that is used together with other wound care measures to treat long-term skin |
Any condition, especially any condition of disease, which renders some particular line of treatment improper or undesirable.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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In medicine, a contraindication (pronounced as contra-indication) is a condition or factor that increases the risks involved in using a particular Drug
Some contraindications are absolute, meaning that there are no reasonable circumstances for undertaking a course of action. For example, a baby with a fever should never be given aspirin because of the risk of Reye's syndrome, and a person with an anaphylactic food allergy should never eat that food. Similarly, a person with Hemochromatosis should not be administered iron preparations.
Other contraindications are relative, meaning that the patient is at higher risk of complications, but that these risks may be outweighed by other considerations or mitigated by other measures. For example, a pregnant woman should normally avoid getting X-rays, but the risk may be far less than the risk of not diagnosing or being able to treat a serious condition such as tuberculosis or a broken bone.
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