<dermatology> A group of cutaneous disorders characterised by increased or aberrant keratinisation, resulting in noninflammatory scaling of the skin. Many different metaphors have been used to describe the appearance and texture of the skin in the various types and stages of ichthyosis, for example alligator, collodion, crocodile, fish and porcupine skin. most ichthyoses are genetically determined, while some may be acquired and develop in association with various systemic diseases or be a prominent feature in certain genetic syndromes. The term is commonly used alone to refer to i. Vulgaris.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
| Ichthyosis Classification and external resources |
|
| ICD-10 |
Q80. |
|---|---|
| ICD-9 | 757.1 |
| DiseasesDB | 6646 |
| MeSH | D007057 |
 |
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Ichthyosis is a heterogeneous family of more than 30, generalized, mostly genetic skin disorders. The word comes from [] ιχθύωση and Ancient Greek ιχθύς, „fish“. The most common type of ichthyosis is Ichthyosis vulgaris
There are more than 30 types of ichthyosis. The most common ones are:
Non-congenital ichthyoses (vulgar ichthyosis, not visible at birth, develops within the first months after birth)
Congenital ichthyoses (present at the day of birth)
Ichthyoses with additional characteristics
Non-genetic ichthyoses
A physician often can diagnose ichthyosis by looking at the skin. A family history is also very useful. In some cases, a skin biopsy will be done to help to confirm the diagnosis. In a biopsy, a small piece of skin is removed and examined under a microscope. In some instances, genetic testing may be helpful in making a diagnosis. Ichthyosis is not more or less common in any ethnic group. As of now, there is no way to prevent ichthyosis.
Treatments for ichthyosis often take the form of topical application of creams and emollient oils, in an attempt to hydrate the skin. Retinoids are also used for some conditions. Exposure to sunlight may improve or worsen the condition.
There can be ocular manifestations of ichthyosis, such as corneal and ocular surface diseases. Vascularizing keratitis, which is more commonly found in congenital keratitis-ichythosis-deafness (KID), may worsen with isotretinoin therapy.
Ichthyosis or ichthyosis-like diseases exist for several types of animals, including cattle, chickens, llamas, mice and dogs. [2] Ichthyosis of varying severity is well-documented in some popular breeds of domestic dogs. The most common breeds in which this condition manifests itself are Golden retrievers, American bulldogs, Jack Russell terriers, and Cairn terriers. [3]
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