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Suprofen

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Definition from OMD (Online Medical Dictionary):

suprofen

<chemical> Alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid. An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.

Pharmacological action: non-steroidal anti-inflammatory agents, cyclooxygenase inhibitors.

Chemical name: Benzeneacetic acid, alpha-methyl-4-(2-thienylcarbonyl)-

(12 Dec 1998)



Suprofen
Systematic (IUPAC) name
2-(4-Thiophen-2-ylcarbonylphenyl)propanoic acid
Identifiers
CAS number 40828-46-4
ATC code M01AE07
PubChem 5359
Drug Bank APRD00230
Chemical data
Formula C14H12O3S 
Mol. mass 260.309 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 20%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Suprofen is an NSAID marketed in a 1% solution under the trade name Profenal.


Uses

Suprofen was originally used as a tablet but has since been discontinued in that form.[1] It is now used exclusively as a Topical ophthalmic solution, typically to prevent miosis during and after ophthalmic surgery.






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